Microscopy-Guided 3-D Reconstruction of Nanodendrites in Biosensors

Nanodendritic structures have gained increasing popularity in electrochemical sensors. However, it is still rare to generate a 3-D model short period of time understand the structure–function relationship Here, we report construction for nanodendritic, metallic frequently grown on top bioelectronics. This achieved by merging two sources 2-D dendritic information, which includes top-view images from scanning electron microscopy (SEM) and side-view visualization Monte Carlo simulations. The provide boundary conditions tune simulations construct morphology. We validated comparing area densities predicted via this with those computed images. In addition, tuning simulation parameters can be used find optimized density, an essential indicator sensitivity enhancement. success provides means limits bioelectronics through growth without need time-consuming sensor fabrication testing. Furthermore, our SEM-guided technique significant resemblance experimental It possesses potential applications morphological investigations future biosensor design.